CHM-260 Fundamental Biochemistry
Course Description: Structures, properties, and functions of
proteins, enzymes, nucleic acids, carbohydrates, and lipids; the utilization
and synthesis of these materials by living systems and the relationship of the
processes to energy production and utilization.
Prerequisites: CHM230 and CHM230LL, or CHM236 and CHM236LL
Announcements
Some more problem sets below.
Scroll down for the link to
the Protein Database, along with some specific links to various proteins.
Here is the link the YouTube
animation for ATP synthase.
Here is the key for Quiz #4.
Problem Sets
Chapter 1 – Review Questions
Functional
Groups: 4, 11
Biomolecules: 5, 7, 13, 21
Atoms
and ions: 18
Definitions: 6a-c, 6e-j, 14a-b, 14d-e
Reaction types: 17, 19
Polypeptides: 20
Chapter 1 – Thought Questions
Functional
Groups: 4, 5, 6
Cells: 1,3
Chapter 2 – Review Questions
Organelles: 13, 14, 15
Chapter 2 – Thought Questions
Cell
structure: 4
Chapter 3 – In-chapter Questions
Noncovalent interactions:
2
Chapter 3 – Review Questions
Acidity
and basicity:
1, 2, 16
Noncovalent interactions:
5, 8, 10, 12
Definitions: 11a-b, 11g-j
Chapter 3 – Thought Questions
Water: 8, 9, 12
Chapter 4 – In-chapter Questions
ATP: 2
Chapter 4 – Review Questions
Definitions: 1a-f
Coupled
reactions: 3
Thermodynamics: 6, 8
Chapter 4 – Thought Questions
Thermodynamics: 3, 4, 5, 6
Chapter 5 – In-chapter Questions
Amino
Acids: 1, 2
Polypeptides: 3, 5
Disulfides: 4
Secondary
structures: 7, 8
Chapter 5 – Review Questions
Amino
acids: 2
Definitions: 1, 8, 9
Charges: 3, 4
Polypeptides: 5, 6, 7
pK and pI: 14, 21
Structure: 10, 11, 12
Characterization: 20, 22
Chapter 5 – Thought Questions
Amino
acids: 1, 5, 6
Protein
structure: 4
Chapter 6 – In-chapter Questions
1,
2, 3, 4, 5, 6, 8
Chapter 6 – Review Questions
Definitions:
1a-d
Enzyme
properties: 2, 3, 4, 5, 6, 10, 11, 12,
15
Chapter 7 – In-chapter Questions
Structure: 1, 2, 3, 4, 5, 6
Reactions: 7
Chapter 7 – Review Questions
Structure: 1, 2, 3, 6, 8, 9, 10, 19, 20
Classification: 4, 5, 12, 13
Reactions: 7, 11, 14, 16
Chapter 7 – Thought Questions
1,
2, 3, 6, 7, 8
Chapter 8 – In-chapter Questions
1,
3, 4, 5, 7
Chapter 8 – Review Questions
2g,
6, 10, 12
Chapter 8 – Thought Questions
6,
7
Chapter 9 – In-chapter Questions
Redox: 1, 2, 3, 4
TCA
cycle: 5, 7
Chapter 9 – Review Questions
1a,
1d-g, 3, 4, 5, 9
Chapter 10 – In-chapter Questions
1,
2, 3
Chapter 10 – Review Questions
1a-c,
1j-l, 2, 4, 6
Chapter 11 – In-chapter Questions
1,
2, 3, 4, 5
Chapter 11 – Review Questions
1a,
1c-e, 1j, 2, 3, 13, 14
Chapter 11 – Thought Questions
7
Links:
Protein
Structure Tutorial You will need to download the free Chime
plug-in to view this.
http://www.rcsb.org/pdb/Welcome.do
This links to the RCSB protein structure database. It's a fun site for
examining the structures of proteins. You can highlight types of
residues, look at stereoimages, rotate the
structures, etc.
Some of the specific
structures we’ve looked at so far on the PDB (with the specific codes):
EF hand example:
1psr
Leucine zipper: 1u2u
Zn finger: 1hvo
Alpha-helix: 1k6f
Beta-keratin: 1r6v
Myoglobin: 2jho
Hemoglobin: 1o1j
http://micro.magnet.fsu.edu/electromag/java/atomicorbitals/
This site shows images of s, p , d, and
f atomic orbitals. You can view them
individually or several at a time. Keep in mind that we will deal mainly
with hybridization of just the s and p atomic orbitals.
Take a look at the f-orbitals just for fun.
http://www.orbitals.com/orb
This website has images of various atomic orbitals,
but not just s, p , d, and f orbitals.
It even shows images of more complicated orbitals.
http://www.wpbschoolhouse.btinternet.co.uk/page14/page14.htm
This site has some self-tests for functional group determination. It
makes for a good review.
Some more interesting links:
http://science.nasa.gov/Realtime/jtrack/3d/JTrack3d.html
Choose
your favorite satellite and see where it is. This site shows the current
location of
hundreds of
satellites in orbit around Earth.
http://www.lehsd.k12.nj.us/Pinelands/slideshow/sld001.htm
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