Worksheet VII:  Respiratory System

1.   _________________________ is when air is moved in and out of the lungs.
2. __________________________ is when gases are exchanged between alveoli and blood.
3. __________________________ is when gases are exchanged between body tissues and the blood.
4.  Name the 3 major metabolic pathways of cellular respiration. _______________________________
                                _______________________________
                                _______________________________
5. List, in the correct sequence, the major structures that air passes through to get into the lungs.
                                __________external nares__________
                                _______________________________
                                _______________________________
                                _______________________________
                                _______________________________
                                _______________________________
                                _______________________________
                                ____________lungs_______________
6. List 5 functions of the nose or nasal cavity.            _______________________________
                                _______________________________
                                _______________________________
                                _______________________________
                                _______________________________
7. Name the 3 bones and kind of cartilage that forms the nose.    _______________________________
                                _______________________________
                                _______________________________
                                _______________________________
8. The external openings to the nasal cavity are called __a__ and the openings leading into the pharynx are called __b__.
    a. ______________________________        b. _______________________________

9.  The __a__ divides the nasal cavity.  It is formed by __b__ anteriorly and the __c__  and __d__ of the ethmoid bone posteriorly.
    a. ______________________________        c. _______________________________
    b. ______________________________        d. _______________________________

10. Name 4 bones that house paranasal sinuses.        _______________________________
                                _______________________________
                                _______________________________
                                _______________________________

11.  Give 4 functions of the paranasal sinuses.           
                                _______________________________
                                _______________________________
                                _______________________________
                                _______________________________

12. Identify the disorder of the respiratory tract based on the information given below.
    a. Introduction of air into thoracic cavity.                  _______________________________
    b. Repeated cycle of irregular breathing; normal in
    infants; diagnostic of pulmonary and other diseases in
    adults.                                                                        _______________________________
    c. Inflammation of pleura linings due to decreased
    secretion of serous fluid.                                            _______________________________
    d. Inflammation of nasal mucosa that causes release
    of excessive mucus.                                                   _______________________________
    e. Inflammation of sinuses that causes release of
    excessive mucus.                                                       _______________________________
    f. Entry of blood into pleural cavity.                          _______________________________
    g. Deficiency of surfactant in infants causes breathing
    to become increasingly more difficult.                       _______________________________
    h. Inflammation of the vocal cords.                           _______________________________

13.  The __________________________ leads from the medial surface of the eye into the nasal cavity.

14.  The __a__ and __b__ nasal conchae bones are part of the __c__ bone while the __d__ nasal concha
is a separate bone.  These bones bear highly __e__ linings that helps __f__ air.
    a. ______________________________        d. _______________________________
    b. ______________________________        e. _______________________________
    c. ______________________________        f. _______________________________

15. Most of the epithelium of the respiratory tract is __a__.  Some of these cells bear __b__ to sweep out
debri trapped by other cells that secrete mucus.  The mucus-secreting cells are called __c__ cells.
    a. ______________________________        c. _______________________________
    b. ______________________________    

16. The pharynx is composed of 3 regions.  They are:       
                                _______________________________
                                _______________________________
                                _______________________________

17. Identify the region of the pharynx based on the information given below.
    a. Lowermost region; from hyoid to larynx.                      _______________________________
    b. Respiratory and digestive tracts completely separate.    _______________________________
    c. Stratified squamous epithelium; palatine and lingual
    tonsils present.                                                                   _______________________________
    d. From soft palate to epiglottis.                                         _______________________________
    e. Auditory (Eustachian) tubes open into this cavity.         _______________________________
    f. Uvula blocks during swallowing.                                   _______________________________

18.  The __a__, or voice box, is supported by __b__ (Give number.) cartilages.  The most prominent
of these is the __c__ cartilage, also commonly called the __d__.  The __c__ cartilage is noticeably
larger in adult males.  Below the __c__ cartilage is the __e__ cartilage.  The __e__ cartilage connects
to the __f__ that divides into __g__ going to each lung.  The opening to the __a__ is called the __h__. 
A third flap of elastic cartilage, called the __i__, covers this opening.  The 4th cartilage of note is the
__j__ cartilage.  It holds paired strips of stratified squamous epithelium, commonly called __k__, in place.
    a. ______________________________        f. _______________________________
    b. ______________________________        g. _______________________________
    c. ______________________________        h. _______________________________
    d. ______________________________        i. _______________________________
    e. ______________________________        j. _______________________________
                                                                           k. _______________________________

19. The epithelium of the larynx changes from _________________________________ to
____________________________ near the end.

20.  Sound __a__ in one's larynx is created by tension on the __b__ and the size of the larynx and thickness
of the __b__.  __c__ is created by the amount of air passing over the __b__.  Sound __d__ is added by the
lips, tongue, and palate.
    a. ______________________________        c. _______________________________
    b. ______________________________        d. _______________________________

21.  The tube that leads from the larynx to the top of the lungs is called the: ______________________.

22.  The __a__, or windpipe, is lined by __b__ epithelial cells.  It is composed of __c__ (Give number.)
__d__ (Give shape.) cartilage rings.  __e__ connective tissue and __f__ muscle also give this structure
flexibility for dilation and constriction.
    a. ______________________________        d. _______________________________
    b. ______________________________        e. _______________________________
    c. ______________________________        f. _______________________________

23. The trachea divides into __a__ that enter the right and left lungs.  __a__ divide into __b__. Both __a__
and __b__ have cartilage rings present. By about 1 mm in diameter the cartilage rings are no longer present
and the tubes are called __c__.  Each __c__ enters a lobule within the lung and divides into narrower __d__. 
__d__ end in grape-like clusters of sacs called __e__.
    a. ______________________________        d. _______________________________
    b. ______________________________        e. _______________________________
    c. ______________________________

24. The right lung has __a__ (Give number.) main lobes: the __b__, __c__, and __d__.  The left lung has
no __c__ lobe and has a depression where the heart sits called the __e__.
    a. ______________________________        d. _______________________________
    b. ______________________________        e. _______________________________
    c. ______________________________

25. Serous membranes associated with the lungs and surrounding thoracic cavity are called __a__.  The
__a__ on the lung's surface are called __b__ and the __a__ lining the thoracic cavity are called __c__. 
The space between the __b__ and __c__ is called the __d__.
    a. ______________________________        c. _______________________________
    b. ______________________________        d. _______________________________

26. Give 3 functions of the pleurae and pleural cavity.       
                                _______________________________
                                _______________________________
                                _______________________________

27.  __a__ are dead end sacs at the end of terminal bronchioles.  This is the site of __b__ (Give function.).
__a__ are surrounded by a network of __c__ and __d__ fibers.  The membrane lining is __e__ epithelium. 
__f__ cells are scattered among the __e__ cells and secrete an oily mixture of phospholipids called __g__. 
__g__ reduces __h__ between cells in the __a__ and prevents the collapse of __a__.  Macrophage cells,
called __i__ cells, patrol the epithelium to prevent bacteria invasion.
    a. ______________________________        e. _______________________________
    b. ______________________________        f. _______________________________
    c. ______________________________        g. _______________________________
    d. ______________________________        h. _______________________________
                                                                            i. ________________________________

28. The movement of air into and out of the lungs is called __a__. __a__ occurs in two stages.  __b__ moves
air into the lungs while __c__ moves air out of the lungs.
    a. ______________________________        c. _______________________________
    b. ______________________________    

29. Atmospheric pressure at sea level is:            ______________________________.

30.  a. _______________________Law states that the pressure of a gas in a closed container is    
       inversely proportional to the volume of that container. This Law is represented by the formula _______________.
    b. If the size (volume) of the container decreases, gas pressure will:    ___________________________.
    c. If the pressure on the gas decreases, gas volume will:            ________________________________.
    d. Calculate the pressure where P1 = 760 mmHg, V1 = 4 liters, V2 = 5 liters. _____________________
    e. Calculate the volume where P1 = 760 mmHg, V1 = 4 liters, P2 = 750 mmHg  __________________

31.  During quiet inspiration 2 muscle groups must contract.  They are the:
                                ________________________________
                                ________________________________

32. During labored inspiration 3 additional muscle groups must contract. Name 2.
                                ________________________________
                                ________________________________

33.  For air to move into the lungs, air pressure in the lungs (alveoli) must be __a__ (lower than/higher
than/the same as) atmospheric pressure.  For the lungs to have a pressure that is __b__ (lower than/higher
than/similar to) atmospheric pressure, the size of the thoracic cavity must __c__ (increase/decrease/remain
the same).
    a. ______________________________        c. _______________________________
    b. ______________________________

34. During inspiration, the diaphragm goes from a(n) __a__ shape to a __b__ shape.  The __c__ muscles
push the __d__ forward and the __e__ up. Both of these muscle contractions result in a(n) __f__ (increase/decrease)
 in size of the thoracic cavity. As the thoracic cavity __f__ in volume, the pressure in the pleural cavity, called __g__
 pressure, __h__ (increases/decreases) from __i__ to __j__ mmHg.  The walls of the lungs are __k__ (sucked
outward/pulled inward) by the pleural membranes.  This event causes pressure in the alveoli, called __l__ pressure
to __m__ (increase/decrease) from __n__ to __o__ mmHg.  Air, consequently, __p__ (rushes in/is pushed out).
    a. ______________________________        i. _______________________________
    b. ______________________________        j. _______________________________
    c. ______________________________        k. _______________________________
    d. ______________________________        l. _______________________________
    e. ________________________________    m. ________________________________
    f. ______________________________        n. _______________________________
    g. ______________________________        o. _______________________________
    h. ______________________________        p. _______________________________

35. Expiration is a(n) __a__ process.  It occurs when the __b__ tissue of the lungs collapses, the __c__ and
__d__ muscles relax.  The size of the thoracic cavity is __e__ (increased/decreased) which causes intrapleural
pressure to __f__ (increase/decrease) from __g__ to __h__.  Intrapulmonary pressure also __i__ (increases/decreases)
from __j__ to __k__ and as a result __l__ (pulls air in/drives air out).
    a. ______________________________        g. _______________________________
    b. ______________________________        h. _______________________________
    c. ______________________________        i. _______________________________
    d. ______________________________        j. _______________________________
    e. ________________________________    k. ________________________________
    f. ______________________________        l. ________________________________

36. _____________________ prevents collapse of the alveoli and sticking after expiration.

37. Identify the lung volumes based on the information given below.
    a.  Air in nose, pharynx, larynx, trachea, bronchi; ~ 150 ml.         _______________________________
    b. Sum of inspiratory reserve, tidal volume, and expiratory
    reserve.                                                                                          _______________________________
    c. Volume of air moved in and out of the lungs during
    normalquiet breathing.                                                                   _______________________________
    d. Volume is ~ 500 ml.                                                                  _______________________________
    e. Volume of air forced out of the lungs in addition to
    tidal volume.                                                                                  _______________________________
    f. Volume of air left in lungs after a forced expiration.                  _______________________________
    g. Volume is ~ 3100 ml.                                                                _______________________________
    h.  Volume of air in addition to tidal volume inspired during
    a deep breath.                                                                                _______________________________
    i. Volume is ~ 1200 ml.                                                                _______________________________
    j. Volume is ~ 4800 ml.                                                                _______________________________

38.  ______________________________ states that the total pressure exerted by a mixture of gases is the sum
of the pressures exerted by each gas in the mixture.

39. Calculate the partial pressures of the following gases.
    a. Nitrogen; 79%.                   _______________________________
    b. Oxygen; 21%.                    _______________________________
    c. Carbon dioxide; 0.04%.     _______________________________
    d. Argon; 1%.                        _______________________________

40. ___________________ Law states that when a mixture of gases, with ~ equal solubilities, is in contact with a
liquid, each gas will dissolve into the liquid in direct proportion to its partial pressure.

41. List 5 factors that affect the diffusion rate of a gas across membranes and give the relationship (e.g. if factor is
high, then the diffusion rate will be slowed.)
            Factor                        Relationship
    ______________________________    ____________________________________________
    ______________________________    ____________________________________________
    ______________________________    ____________________________________________
    ______________________________    ____________________________________________
    ______________________________    ____________________________________________

42. Why does carbon dioxide move across membranes at a rate similar to oxygen, yet oxygen has a partial pressure
many times that of carbon dioxide.__________________________________________
_____________________________________________________________________

43. Give the approximate partial pressures for gases in the specified areas.
    a. pO2 alveolar capillaries (arterial end)                _________________________
    b. pCO2 alveolar capillaries (arterial end).            _________________________
    c. pO2 alveoli.                                                       _________________________
    d. pCO2 alveoli.                                                    _________________________
    e. pO2 in the atmosphere.                                      _________________________
    f. pCO2 in the atmosphere.                                    _________________________
    g. pO2 arterial end of capillary in body tissues.     _________________________
    h. pCO2 arterial end of capillary in body tissues.  _________________________
    i. pO2 venous end of capillary in body tissues.     _________________________
    j. pCO2 venous end of capillary in body tissues.  _________________________
    k. pO2 in a body cell before exchange.                _________________________
    l. pCO2 in a body cell before exchange.                _________________________

44. Give the direction the gas moves from the specified area.
    a. Oxygen movement between alveolus and capillary in alveolus.    _________________________
    b. Carbon dioxide movement in alveolar capillary.                           _________________________
    c. Oxygen movement in arterial end of capillary of body tissue.       _________________________
    d. Carbon dioxide movement in arterial end of capillary of body tissue. ______________________

45. Name the 2 ways oxygen is carried in the blood, listing the most common method of transport first.
                                ________________________________
                                ________________________________

46.  Complete the following reaction:   Hb  +  02  ------->  _________________________  and _________.

47.  Hemoglobin binds with oxygen forming __a__.  Binding of the first oxygen molecule causes a(n) __b__
change in the hemoglobin molecule making it __c__ (easier/harder) to pick up another oxygen. The maximum
number of oxygen molecules carried by one hemoglobin is __d__.  In a high concentration of oxygen molecules
we say that hemoglobin has a __e__ (high/low) affinity for oxygen molecules.
    a. ______________________________        c. _______________________________
    b. ______________________________        d. _______________________________
                                                                            e. _______________________________

48.  The state of attraction of hemoglobin for a particular molecule is its __________________.

  For questions 49 through 55 refer to the oxygen dissociation curve above.
49.  Give the % saturation for the hemoglobin molecules for the partial pressures listed below.
    a. 10 mmHg            __________________
    b. 20 mmHg            __________________
    c. 30 mmHg             __________________
    d. 40 mmHg            __________________
    e. 50 mmHg            __________________
    f. 60 mmHg            __________________
    g. 70 mmHg            __________________
    h. 80 mmHg            __________________
    i. 90 mmHg            __________________
    j. 100 mmHg            __________________

50.  The slope of the curve is steepest between: _________________ (10 and 50 mmHg/ 60 and 80 mmHg/ 80
and 100 mmHg).

51. Hemoglobin is nearly 95% saturated at what partial pressure?    _________________________

52. At sea level, what partial pressure is hemoglobin exposed to in the alveolar capillary? ____________

53. At higher altitudes what happens to partial pressure? _________________  
    Providing the partial pressure of oxygen doesn't drop below 70 mmHg, is there enough oxygen to   
         meet your body's minimum needs?                          _________________
    At what altitude would a partial pressure of 70 mmHg
        be encountered?                                                        __________________.

54. Hemoglobin is nearly ___a__% saturated before entering tissue capillaries and __b__% saturated when leaving
the tissue capillaries.  This per cent saturation when leaving the tissue capillaries is called the __c__.
    a. ______________________________        c. _______________________________
    b. ______________________________

55.  Assuming the temperature at which the dissociation curve was generated was 38 C, what will happen to the curve at 40 C?                     ___________________________________

56. Assuming the pH at which the dissociation curve was generated was 7.4, what will happen to the curve at a pH of 7.2?                    ___________________________________

57.  What will happen to the dissociation curve if H+ ions are released?
  ___________________________________

58. Where would a curve for fetal hemoglobin be located on the graph in reference to the plotted curve?
The curve would be: to the left/right on the plotted curve/to the right. _________________________

59.  When Hydrogen ions bind to hemoglobin, the hemoglobin molecule changes __a__ and has a(n) __b__
(increased/decreased) affinity for __c__. The effect described in the first sentence is called the __d__ effect. 
The __d__ effect occurs in the __e__ (alveolar capillary/tissue capillary).  This effect makes it __f__ (easier,
more difficult) for __c__ to unload.  In the __g__  (alveolar capillary/tissue capillary) Hydrogen ions are removed. 
This allows the hemoglobin molecule to change __a__ and __h__ (increases/decreases) its affinity for __c__. This
effect, called the __i__ effect, is driven partially by the __j__ (higher/lower) partial pressures of oxygen in the __k__
(alveolus/tissue cell).
    a. ______________________________        g. _______________________________
    b. ______________________________        h. _______________________________
    c. ______________________________        i. ________________________________
    d. ______________________________        j. ________________________________
    e. ______________________________        k. _________________________________
    f. _______________________________    

60.  __a__ is an unique intermediate compound of glycolysis that __b__ (enhances/decreases) oxygen release from hemoglobin.
    a. ______________________________        b. ________________________________

61. Carbon monoxide has ___________ times the affinity for hemoglobin compared to oxygen.

62.  List the 3 ways carbon dioxide is transported from the body tissues and give the approximate percentages of each.               
                        % __________      _____________________________
                        % __________      _____________________________
                        % __________      _____________________________

63.  Complete the following reactions with the formula and name of the molecule:
    CO2   +   H2O   ----- (__a__)-----> __b__ ------->    __c__   +   __d__.
    a. Give enzyme:___________________        c. _______________________________
    b. ______________________________        d. _______________________________

64.  The reaction in question #63 is the trigger for the ______________ effect.  This effect makes it
___________________ (easier/more difficult) for hemoglobin to unload oxygen.

65.  The reaction in question #63 occurs a 1000 times faster in RBCs because:
                        ___________________________________________.

66.  As bicarbonate ions are formed in the RBC, they diffuse out into the __a__.  Because there is a net loss of __b__
(positive/negative) charges in the RBC, a(n) __c__ (positively/negatively) charged __d__ ion diffuses in to compensate. 
This event is called the __e__.
    a. ______________________________        d. _______________________________
    b. ______________________________        e. _______________________________
    c. ______________________________
67. Where does the sequence, described in question 66, occur:  in the tissue capillary or the alveolar capillary?                           
_______________________________

68. Briefly describe what happens in the other area from your answer in question 67.
___________________________________________________________________________________
___________________________________________________________________________________

69. The control center for respiration is in the __a__ of the __b__ and __c__.  The __b__ has inspiratory and
expiratory centers while the __c__ has pneumotaxic and apneustic centers.
    a. ______________________________        c. _______________________________
    b. ______________________________    

70. Identify the respiratory control center described below and also given its location in the medulla or pons.
    a. Continuously stimulates inspiratory center; prolongs
    inspiration when holding your breath.                    ______________________________
    b. Superiorly located on brainstem; continuously
    inhibits inspiratory center; fine tunes breathing rhythm
    and prevents lungs from overinflating.                   ______________________________
    c. Has both inspiratory and expiratory neurons present;
    important in forced expiration.                                ______________________________
    d. Neurons myogenic; expands thoracic cavity by sending
    impulses to diaphragm and external intercostals.     ______________________________

71. List 3 factors that influence the rate and depth of breathing.   
                                ______________________________
                                ______________________________
                                ______________________________

72. Which chemical factor is the most potent?            ______________________________

73. Name 2 places chemoreceptors are located.            ______________________________
                                                                                      ______________________________

74. Identify the terms associated with breathing from the definitions given below.
    a.  Normal quiet breathing.                                    ______________________________
    b. Rapid breathing.                                                ______________________________
    c. Deficiency of oxygen.                                       ______________________________
    d. Rate of respiration is higher than that required to
    maintain normal level of plasma carbon dioxide.  ______________________________
    e. An abnormal increase in the amount of carbon
      dioxide in the blood.                                            ______________________________
    f. An abnormal decrease in the amount of carbon
        dioxide in the blood.                                          ______________________________
    g. Lack of adequate oxygen at the tissue level.     ______________________________
    h. Unconsciousness due to interference with
        oxygen supply of the blood.                              ______________________________
    i. Painful or labored breathing.                              ______________________________
    j. Temporary cessation of breathing.                     ______________________________

75. What effects does smoking have on the respiratory system? _______________________________
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76.  Why does a pneumothorax caused breathing difficulty? __________________________________
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77. Why is expiration a passive process? _________________________________________________
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78. Why is breathing difficult with declining levels of surfactant? ______________________________
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79. Why is breathing more difficult on a 110 F day compared to a day at 80 F? ___________________
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80. Why do most people traveling to high altitudes have little difficulty breathing even though there is less
oxygen present? ____________________________________________________________________
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81. Why does fetal hemoglobin have a higher affinity for oxygen than maternal hemoglobin? _________
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82.  Could you carry out basic activities (without an oxygen tank and mask) on Mt. McKinley, AK?  Why
or why not? __________________________________________________________________________
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Answers:  Worksheet VII-Respiratory System

1.  Breathing or pulmonary ventilation.
2. External respiration.
3. Internal respiration.
4. Glycolysis, Kreb's Cycle, Electron Transport System.
5.  External nares, nasal cavity, pharynx, larynx, trachea, bronchi, (bronchioles), lungs.
6.  Provides opening for air to enter./Moistens and regulates temperature of air./Filters and cleans air./
Olfaction./Resonating chamber for speech.
7. Nasal, frontal, maxillary bones; hyaline cartilage.
8.     a. nostrils or external nares            b. internal nares (choanae)

9.     a. nasal septum                    c. vomer
        b. hyaline cartilage              d. perpendicular plate
10.  Frontal, sphenoid, ethmoid, and maxillary.
11. Lightens skull./Resonance chambers./Warm and moisten air./Mucus traps debris.
12.   a. Pneumothorax                              e. Sinusitis
        b. Cheyne-Stokes syndrome            f. Hemothorax
        c. Pleurisy                                        g. Respiratory distress syndrome
        d. Rhinitis                                        h. Laryngitis

13. nasolacrimal duct

14. a. superior                    d. inferior
    b. middle                        e. vascular
    c. ethmoid                      f. moisten and/or warm

15.     a. pseudostratified                c. goblet
          b. cilia

16. nasopharynx, oropharynx, laryngopharynx.

17. a. laryngopharynx                d. oropharynx
      b. laryngopharynx                e. nasopharynx
      c. oropharynx                       f. nasopharynx

18.a. larynx                    g. bronchi                   
    b. 9                             h. glottis
    c. thyroid                    i. epiglottis
    d. Adam's apple         j. arytenoid
    e. cricoid                    k. vocal cords
    f. trachea
19. stratified squamous to pseudostratified
20.     a. pitch                              c. Loudness
          b. vocal cords                    d. quality
21. trachea
22.     a. trachea                      d. C shaped
          b. pseudostratified        e. Elastic
          c. 16-20                        f. smooth

23.a. primary bronchi                   d. terminal bronchioles
    b. secondary bronchi                e. alveoli
    c. bronchioles

24.   
    a. 3                               d. inferior
    b. superior                    e. cardiac notch
    c. middle

25. a. pleurae                                  c. parietal pleural (e)
      b. visceral pleural (e)                d. pleural cavity

26. Secretes lubricant./Pressure changes for inspiration and expiration occur there./Separates
lungs from heart.

27.a. Alveoli                         f. Septal
    b. gas exchange                g. surfactant
    c. capillaries                      h. surface tension
    d. elastic                            i. dust
    e.  simple squamous

28.     a. breathing                    c. expiration
          b. Inspiration
29.     760 mmHg    
30.     a. Boyle's Law/P1V1 = P2V2            d. 608 mmHg
          b.  increase                                          e. 4.05 l
          c. increase
31. diaphragm and external intercostals
32. sternocleidomastoid, scalenes, pectoralis minor.
33.     a. lower than                    b. lower than
                                                   c. increase

34 a. dome                                    i. 756 mmHg
    b. flat                                        j. 754 mmHg
    c. external intercostal                k. sucked outward
    d. sternum                                 l. intrapulmonary
    e. ribs                                        m. decrease
    f. increase                                  n. 760 mmHg
    g. intrapleural                            o. 758 mmHg
    h. decreases                               p. rushes in

35.a. passive                    g. 754
    b. elastic                       h. 756
    c. diaphragm                 i. increases
    d. external intercostal    j. 758
    e. decreased                  k. 762
    f. increase                     l. drives air out

36. Surfactant

37.a. Dead air space                f. Residual volume
    b. Vital capacity                   g. Inspiratory reserve
    c. Tidal volume                    h. Inspiratory reserve
    d. Tidal volume                    i. Expiratory reserve and Residual volume*
    e. Expiratory reserve            j. Vital capacity
*Similar volumes, but do not have same definitions.

38. Dalton's law of partial pressures

39.a. 597 mmHg                    c. 0.3 mmHg
    b. 159 mmHg                     d. 7.6 mmHg

40. Henry's law

41.Pressure difference, the greater the difference the faster the rate.
    Surface area, the more surface area the faster the rate.
    Thickness of membrane, the thicker the membrane the slower the rate.
    Solubility, the greater the solubility in a liquid, the faster the rate.
    Temperature, the higher the temperature the faster the rate.
    Molecular weight, the heavier the molecule the slower the rate.

42. Carbon dioxide is much more soluble in liquids than oxygen.

43. a. 40 mmHg                    g. 104 mmHg
    b. 45 mmHg                      h.  40 mmHg
    c. 104 mmHg                    i. 40 mmHg
    d. 40 mmHg                      j. 45 mmHg
    e. 160 mmHg                    k. 40 mmHg
    f.  0.3 mmHg                     l. 45 mmHg

44.     a. From alveolus into capillary            c. Capillary to tissue cell
          b. From capillary into alveolus            d. From tissue cell to capillary

45.     As oxyhemoglobin (98.5 %); dissolved in plasma.

46.     oxyhemoglobin     H+

47.     a.  oxyhemoglobin                c. easier
          b. conformational                  d. 4
                                                        e. high
48. affinity
49.a. 10%                        f. 90%
    b.  37%                        g. 95%
    c. 57%                         h. 97%
    d. 72%                         i.  98%
    e. 83%                         j. 100%
50. 10 and 50 mmHg
51. 70 mmHg
52. 104 mmHg
53. decrease/yes/over 7,000 feet.
54.     a. 100%                    c. venous reserve
    b. 75%
55. Curve shifts to the right-more difficult for oxygen to load.
56. Shifts to the right-more difficult for oxygen to load or easier for oxygen to unload.
57. Same as in answer 56.
58. to the left
59.a. conformation                    g. alveolar capillary
    b. decreased                          h. increases
    c. oxygen                              i. Haldane (Not on test)
    d. Bohr                                  j. higher
    e. tissue capillary                   k. alveolus
    f. easier

60.     a. 2,3 diphosphoglycerate (DPG)        b. enhances
61. 200
62. 60-70% as bicarbonate ion; 23 % with carbaminohemoglobin; 7-10% dissolved in plasma.
63.     a. carbonic anhydrase                   c. Bicarbonate ion HCO3-
          b. carbonic acid (H2CO3)            d. Hydrogen ion H+
64. Bohr/easier
65. RBCs have the enzyme carbonic anhydrase.
66.     a. plasma                       c. negatively
          b. negative                    d. Chloride
                                                e. Chloride shift

67.      in the tissue capillary
68.     In the alveolar capillary, the reaction occurs in the opposite direction, but is still called the chloride     shift.  
69.     a. reticular formation                c. pons
          b. medulla

70.     a. Apneustic center (Pons)         c. Ventral Respiratory Group  (Medulla)
          b. Pneumotaxic center (Pons)    d. Dorsal Respiratory Group (Medulla)
71. Irritants,Strongs emotiom such as pain,Chemicals.
72. CO2
73. Carotid and aortic bodies, hypothalamus.

74.a. Eupnea                    f. Hypocapnia
    b. Hypernea                 g. Hypoxia
    c. Anoxia                     h. Asphyxia
    d. Hyperventilation      i. Dyspnea
    e. Hypercapnia             j. Apnea
75. Smoking destroys the ciliated surface of the trachea, bronchi, and bronchioles making it difficult for the body
to remove dust and debri taken in during breathing.  Additionally, carbon particles from smoke pass into the alveoli
and decrease surface area for gas exchange.  Long-term smoking destroys alveoli resulting in emphysema.
76. When an object punctures the thoracic cavity intrapleural pressure becomes equal to atmospheric pressure. 
Expansion of the lungs during inspiration cannot generate significant pressure difference to allow air to move into the lungs.
77. The lungs have elastic tissue and like a rubber band, once they are stretched, they return to their original size and
expel the air.
78. Surfactant decreases surface tension in the alveoli.  During expiration, the alveoli would stick together and be
difficult to expand with only water in them.  Water molecules create a very high surface tension that would literally
stick the sides of an alveolus together.
79. According to Charles' Law as the temperature of a gas increases, the gas expands.  Cool (80 F) air coming into
the lungs (at 98.6 F) would expand the lungs to some degree even without the aid of the diaphragm and intercostal
muscles.  However, warm (110 F) air coming into the lungs (at 98.6 F) would cool and compress.  Therefore, the
inspiratory muscles have to work harder to overcome the inward force that a compressed gas exerts on the lungs.
80. Even at partial pressures of 50 mmHg for oxygen, hemoglobin is still over 80% saturated.  Only altitudes over
10,000 feet would ever generate such a small partial pressure for oxygen.
81. If fetal hemoglobin did not have a higher affinity for oxygen than maternal hemoglobin, oxygen would never
be released into the fetal circulation through the placental.
82.  Yes, because your hemoglobin is still 75% saturated even at 20,300 feet altitude.  Unless you have trained at
high altitudes, you would not be able to do much, but you (depending on your individual physiological tolerance)
would be able to stay alive.  This also assumes you are well-insulated from the cold, etc.)

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